Found 253 from University of Notre Dame 
Affinity DataKi: 0.470nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.590nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of APMA activated recombinant human full length MMP2 expressed in mouse cells using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substra...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli using McaKPLGL-Dpa-AR-NH2 as substrate...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibition of recombinant human MMP2 expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of human recombinant MMP-8 catalytic domain (99 to 269 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as s...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Binding affinity against opioid receptor mu using [3H]-etorphine as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -10.4kcal/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Affinity DataKi: 28nM ΔG°: -10.2kcal/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of recombinant human MMP2More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain using Mca-PLGL-DpaAR-NH2 as substrate by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 48nM ΔG°: -9.88kcal/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 50nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Compound was evaluated for time-dependent inactivation of Ribonucleotide diphosphate reductase (RDPR) in E. coliMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataKi: 61nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged ADAM17 (Arg215 to Asn671 residues) expressed in baculovirus infected Sf21 cells using Mca-PLAQ...More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:Inhibition assay using matrix metalloproteinase (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Inhibition of recombinant human MMP14 catalytic domain (89 to 265 residues) expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-A...More data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Inhibition of human recombinant MMP2 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataKi: 73nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged ADAM10 (Thr214 to Glu672 residues) expressed in baculovirus infected Sf21 cells using McaKPLG...More data for this Ligand-Target Pair
Affinity DataKi: 75nMAssay Description:Inhibition of recombinant human MMP7 expressed in Escherichia coli using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 as substrate by fluorescence spe...More data for this Ligand-Target Pair
Affinity DataKi: 85nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 88nM ΔG°: -9.52kcal/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Slow binding inhibition of human recombinant MMP14 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 127nMAssay Description:Slow binding inhibition of human recombinant MMP2 using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of human recombinant MMP9 assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
Affinity DataKi: 142nM ΔG°: -9.24kcal/molepH: 7.4 T: 2°CAssay Description:To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...More data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of recombinant human MMP9 expressed in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Slow binding inhibition of human recombinant MMP9 catalytic domain using MOCAc-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH2 substrateMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain assessed as hydrolysis of MOCAcPLGLA2pr(Dnp)AR-NH2 by fluorescence spectrofluorometry More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of human recombinant MMP-9 catalytic domain using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of human recombinant MMP-2 using MOCAcPLGLA2pr(Dnp)AR-NH2 as substrate by fluorescence spectrophotometric analysisMore data for this Ligand-Target Pair
